Medini is located inside the Iskandar Puteri (also known as Nusajaya) flagship zone of Iskandar Malaysia. Medini spans a total of 2,230 acres, an is poised to become the Central Business District of the region. The all-encompassing development, boasts a masterplan of 6 zones, catering to various needs in supporting its vast ecosystem and the international role it aspires to play. Medini will also take on the mission of becoming a Smart City, with the implementation of features like Smart Building, Integrated Operations Centre (initial control centre for Medini Smart City), the Medini Portal Site, and Electric Vehicle (EV) facilities.

Zone A sits on the northernmost tip of Medini, where the 570 acres will host a range of developments, such as the LEGOLAND Resort, Mall of Medini, and will be home to the Urban Wellness project, which has seen the Gleneagles Medini open its doors. A public school, 18 SK Medini is also in the area.

Zone B is slated to become the business and media district of Medini, where its 351-acres will encompass a Commercial Centre, Small Medium Enterprises (SME) Park, hotels, as well as other integrated residential developments like UMCity Medini Lakeside.

Given its vision to become a centre for international trade and business, the 620-acres Zone C will be the Trade and Logistics Zone, providing for the operational aspect of Medini. The zone will offer facilities and services, such as warehouses, transport and freight services, as well as outsourcing of packaging and business process.

In line with the establishment of the Pinewood Iskandar Malaysia Studios in Nusajaya, Zone D of Medini will be the Creative Zone, featuring state-of-the-art infrastructure and technology. This part will appeal to businesses and international companies involved in the sectors of broadcasting, movie production, animation, as well as digital content and creative R&D.

Zone E will comprise of luxury landed developments, as well as high-rises offering condominium residences. Living in this zone of Medini boasts a resort-like ambience, close to the exclusive Horizon Hills Golf and Country Club, as well as a resort. A private school and suburban commercial centre can also be found in this 210-acres region of Medini. Zone F will be the location for the Sunway Iskandar urban integrated township.

Aside from the range of developments and amenities within Medini, it is also within reach of attractions like the LEGOLAND theme park and Sanrio Hello Kitty Town, the EduCity educational hub, the Puteri Harbour waterfront, as well as the new administrative capital, Kota Iskandar.

Medini is located strategically close to key points of domestic and international connectivity, where the Malaysia-Singapore Second Link Causeway is accessible via the Second Link Expressway not too far off. Its location also affords access to 2 international airports, the Senai International Airport (25 minutes) as well as the Changi Airport in Singapore (55 minutes). Seaports within Johor, namely the Tanjung Pelepas, Pasir Gudang, Tanjung Langsat ports, and even the Jurong Port (Singapore) and Port of Singapore Authority are also within reach.

In addition, rail connectivity is also possible, with the existing Keratapi Tanah Melayu (KTM) service connecting to the Thai border up north, while the Rapid Transit System (RTS) link and upcoming KL-Singapore High Speed Rail (HSR) will make cross-border travel and logistics much more convenient. The ferry service which operates between Tanjung Balai, the Singapore Harbour and Batam (Indonesia), is also another practical form of transport.